Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-549 INK-128
3.1623
mTORC1/2
PI3K/mTOR
 0.0717 0.09019
BT-549 PF-4708671
0.001
p70S6K
PI3K/mTOR
 1.0982 0.00119
BT-549 PF-4708671
0.0031623
p70S6K
PI3K/mTOR
 1.0641 0.00694
BT-549 PF-4708671
0.01
p70S6K
PI3K/mTOR
 1.0617 0.00443
BT-549 PF-4708671
0.031623
p70S6K
PI3K/mTOR
 1.0390 0.00132
BT-549 PF-4708671
0.1
p70S6K
PI3K/mTOR
 1.0387 0.00174
BT-549 PF-4708671
0.31623
p70S6K
PI3K/mTOR
 1.0168 -0.00234
BT-549 PF-4708671
1.0
p70S6K
PI3K/mTOR
 0.9959 -0.00221
BT-549 PF-4708671
3.1623
p70S6K
PI3K/mTOR
 0.9686 0.00294
BT-549 PF-4708671
10.0
p70S6K
PI3K/mTOR
 0.7437 0.01657
BT-549 Buparlisib
0.001
pan PI3K
PI3K/mTOR
 1.0597 0.00364
BT-549 Buparlisib
0.0031623
pan PI3K
PI3K/mTOR
 1.0292 0.00192
BT-549 Buparlisib
0.01
pan PI3K
PI3K/mTOR
 0.9997 0.00787
BT-549 Buparlisib
0.031623
pan PI3K
PI3K/mTOR
 1.0300 -0.00469
BT-549 Buparlisib
0.1
pan PI3K
PI3K/mTOR
 0.9398 0.01022
BT-549 Buparlisib
0.31623
pan PI3K
PI3K/mTOR
 0.9148 0.00656
BT-549 Buparlisib
1.0
pan PI3K
PI3K/mTOR
 0.7129 0.05174
BT-549 Buparlisib
3.1623
pan PI3K
PI3K/mTOR
 -0.0053 0.25670
BT-549 Buparlisib
10.0
pan PI3K
PI3K/mTOR
 -0.2716 0.38759
BT-549 Pictilisib
0.001
pan PI3K
PI3K/mTOR
 0.9515 0.00331
BT-549 Pictilisib
0.0031623
pan PI3K
PI3K/mTOR
 0.9497 0.00379
BT-549 Pictilisib
0.01
pan PI3K
PI3K/mTOR
 0.9602 0.01267
BT-549 Pictilisib
0.031623
pan PI3K
PI3K/mTOR
 0.9364 0.00738
BT-549 Pictilisib
0.1
pan PI3K
PI3K/mTOR
 0.8933 0.01189
BT-549 Pictilisib
0.31623
pan PI3K
PI3K/mTOR
 0.8688 -0.00021