Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-549 Torin2
0.00031623
mTOR/ATM/ATR
PI3K/mTOR
 1.0114 -0.00012
BT-549 Torin2
0.001
mTOR/ATM/ATR
PI3K/mTOR
 0.9264 0.01149
BT-549 Torin2
0.0031623
mTOR/ATM/ATR
PI3K/mTOR
 0.7101 0.01464
BT-549 Torin2
0.01
mTOR/ATM/ATR
PI3K/mTOR
 0.5068 0.04208
BT-549 Torin2
0.031623
mTOR/ATM/ATR
PI3K/mTOR
 0.2093 0.05648
BT-549 Torin2
0.1
mTOR/ATM/ATR
PI3K/mTOR
 0.1449 0.10102
BT-549 Torin2
0.31623
mTOR/ATM/ATR
PI3K/mTOR
 0.0638 0.14406
BT-549 Torin2
1.0
mTOR/ATM/ATR
PI3K/mTOR
 -0.0209 0.25500
BT-549 Everolimus
0.001
mTOR1
PI3K/mTOR
 0.6089 0.02695
BT-549 Everolimus
0.0031623
mTOR1
PI3K/mTOR
 0.5766 0.01630
BT-549 Everolimus
0.01
mTOR1
PI3K/mTOR
 0.5609 0.04190
BT-549 Everolimus
0.031623
mTOR1
PI3K/mTOR
 0.5631 0.02794
BT-549 Everolimus
0.1
mTOR1
PI3K/mTOR
 0.5523 0.02931
BT-549 Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.5704 0.02850
BT-549 Everolimus
1.0
mTOR1
PI3K/mTOR
 0.5740 0.03804
BT-549 Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.5296 0.02826
BT-549 Everolimus
10.0
mTOR1
PI3K/mTOR
 0.5197 0.03659
BT-549 INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 0.9825 0.00068
BT-549 INK-128
0.001
mTORC1/2
PI3K/mTOR
 0.9913 0.00247
BT-549 INK-128
0.0031623
mTORC1/2
PI3K/mTOR
 0.9090 0.00698
BT-549 INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.6811 0.01522
BT-549 INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.2948 0.04981
BT-549 INK-128
0.1
mTORC1/2
PI3K/mTOR
 0.1292 0.09278
BT-549 INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.1078 0.07784
BT-549 INK-128
1.0
mTORC1/2
PI3K/mTOR
 0.0882 0.09924