Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MDA-MB-231 Neratinib
0.31623
EGFR/HER2
RTK
 0.9224 0.01639
MDA-MB-231 Neratinib
1.0
EGFR/HER2
RTK
 0.6923 0.04891
MDA-MB-231 Neratinib
3.1623
EGFR/HER2
RTK
 -0.0957 0.37470
MDA-MB-231 Tivantinib
0.001
MET
RTK
 0.9784 0.00388
MDA-MB-231 Tivantinib
0.0031623
MET
RTK
 1.0000 0.00085
MDA-MB-231 Tivantinib
0.01
MET
RTK
 1.0612 -0.00078
MDA-MB-231 Tivantinib
0.031623
MET
RTK
 1.0948 0.00672
MDA-MB-231 Tivantinib
0.1
MET
RTK
 1.0783 0.00440
MDA-MB-231 Tivantinib
0.31623
MET
RTK
 0.6285 0.07435
MDA-MB-231 Tivantinib
1.0
MET
RTK
 0.1165 0.26992
MDA-MB-231 Tivantinib
3.1623
MET
RTK
 -0.0060 0.24654
MDA-MB-231 Tivantinib
10.0
MET
RTK
 -0.0845 0.32048
MDA-MB-231 Cediranib
0.001
VEGFR/cKIT
RTK
 1.0153 -0.00262
MDA-MB-231 Cediranib
0.0031623
VEGFR/cKIT
RTK
 0.9650 0.01017
MDA-MB-231 Cediranib
0.01
VEGFR/cKIT
RTK
 0.9965 0.00160
MDA-MB-231 Cediranib
0.031623
VEGFR/cKIT
RTK
 1.0061 0.00370
MDA-MB-231 Cediranib
0.1
VEGFR/cKIT
RTK
 0.9938 0.01076
MDA-MB-231 Cediranib
0.31623
VEGFR/cKIT
RTK
 0.9749 0.01020
MDA-MB-231 Cediranib
1.0
VEGFR/cKIT
RTK
 0.9710 0.01130
MDA-MB-231 Cediranib
3.1623
VEGFR/cKIT
RTK
 0.8379 0.02301
MDA-MB-231 Cediranib
10.0
VEGFR/cKIT
RTK
 -0.3620 0.52491
MDA-MB-231 Cabozantinib
0.001
VEGFR2/MET
RTK
 0.9775 0.00709
MDA-MB-231 Cabozantinib
0.0031623
VEGFR2/MET
RTK
 1.0047 0.00225
MDA-MB-231 Cabozantinib
0.01
VEGFR2/MET
RTK
 0.9898 0.00614
MDA-MB-231 Cabozantinib
0.031623
VEGFR2/MET
RTK
 0.9652 0.00580