Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

 Full screen view
Filter results: >>>>
Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MDA-MB-231 Cabozantinib
0.1
VEGFR2/MET
RTK
 0.9003 0.01079
MDA-MB-231 Cabozantinib
0.31623
VEGFR2/MET
RTK
 0.9075 0.01176
MDA-MB-231 Cabozantinib
1.0
VEGFR2/MET
RTK
 0.8295 0.02161
MDA-MB-231 Cabozantinib
3.1623
VEGFR2/MET
RTK
 0.7464 0.03033
MDA-MB-231 Cabozantinib
10.0
VEGFR2/MET
RTK
 0.0749 0.20683
SK-BR-3 Abemaciclib
0.001
CDK4/6
Cell cycle
 0.8713 0.00683
SK-BR-3 Abemaciclib
0.0031623
CDK4/6
Cell cycle
 0.8677 0.00360
SK-BR-3 Abemaciclib
0.01
CDK4/6
Cell cycle
 0.6078 0.02548
SK-BR-3 Abemaciclib
0.031623
CDK4/6
Cell cycle
 0.4834 0.03495
SK-BR-3 Abemaciclib
0.1
CDK4/6
Cell cycle
 0.3966 0.03986
SK-BR-3 Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.3432 0.03985
SK-BR-3 Abemaciclib
1.0
CDK4/6
Cell cycle
 0.2397 0.06137
SK-BR-3 Abemaciclib
3.1623
CDK4/6
Cell cycle
 0.2641 0.04005
SK-BR-3 Abemaciclib
10.0
CDK4/6
Cell cycle
 0.1432 0.09666
SK-BR-3 Palbociclib
0.00031623
CDK4/6
Cell cycle
 1.0488 -0.00133
SK-BR-3 Palbociclib
0.001
CDK4/6
Cell cycle
 1.0312 0.00420
SK-BR-3 Palbociclib
0.0031623
CDK4/6
Cell cycle
 0.9382 0.00629
SK-BR-3 Palbociclib
0.01
CDK4/6
Cell cycle
 0.8604 0.01204
SK-BR-3 Palbociclib
0.031623
CDK4/6
Cell cycle
 0.7121 0.01774
SK-BR-3 Palbociclib
0.1
CDK4/6
Cell cycle
 0.5749 0.03075
SK-BR-3 Palbociclib
0.31623
CDK4/6
Cell cycle
 0.4332 0.04315
SK-BR-3 Palbociclib
1.0
CDK4/6
Cell cycle
 0.4712 0.03549
SK-BR-3 Palbociclib
3.1623
CDK4/6
Cell cycle
 0.3503 0.04754
SK-BR-3 AZD7762
0.001
CHK1/2
Cell cycle
 1.1677 0.00763
SK-BR-3 AZD7762
0.0031623
CHK1/2
Cell cycle
 1.1657 0.01045