Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| MDA-MB-231 | Cisplatin | 1.0 | Chemo | Chemotherapy | 0.7698 | 0.00638 |
| MDA-MB-231 | Cisplatin | 3.1623 | Chemo | Chemotherapy | 0.4287 | 0.03823 |
| MDA-MB-231 | Cisplatin | 10.0 | Chemo | Chemotherapy | 0.2721 | 0.03863 |
| MDA-MB-231 | Doxorubicin | 0.00031623 | Chemo | Chemotherapy | 0.9126 | 0.00521 |
| MDA-MB-231 | Doxorubicin | 0.001 | Chemo | Chemotherapy | 0.9318 | 0.00042 |
| MDA-MB-231 | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.7149 | 0.04644 |
| MDA-MB-231 | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.1361 | 0.18130 |
| MDA-MB-231 | Doxorubicin | 0.031623 | Chemo | Chemotherapy | -0.0177 | 0.10321 |
| MDA-MB-231 | Doxorubicin | 0.1 | Chemo | Chemotherapy | -0.0903 | 0.16988 |
| MDA-MB-231 | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.1811 | 0.28406 |
| MDA-MB-231 | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.2501 | 0.39444 |
| MDA-MB-231 | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.4864 | 0.69790 |
| MDA-MB-231 | Taxol | 0.0001 | Chemo | Chemotherapy | 0.7633 | 0.02094 |
| MDA-MB-231 | Taxol | 0.00031623 | Chemo | Chemotherapy | 0.9486 | 0.01025 |
| MDA-MB-231 | Taxol | 0.001 | Chemo | Chemotherapy | 0.7873 | 0.07047 |
| MDA-MB-231 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.3793 | 0.25412 |
| MDA-MB-231 | Taxol | 0.01 | Chemo | Chemotherapy | 0.0831 | 0.37519 |
| MDA-MB-231 | Taxol | 0.031623 | Chemo | Chemotherapy | -0.0107 | 0.41404 |
| MDA-MB-231 | Taxol | 0.1 | Chemo | Chemotherapy | -0.0493 | 0.38815 |
| MDA-MB-231 | Taxol | 0.31623 | Chemo | Chemotherapy | -0.0762 | 0.36779 |
| MDA-MB-231 | Taxol | 1.0 | Chemo | Chemotherapy | -0.1204 | 0.41739 |
| MDA-MB-231 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.9754 | -0.00362 |
| MDA-MB-231 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.9251 | 0.00105 |
| MDA-MB-231 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.7952 | 0.00267 |
| MDA-MB-231 | Topotecan | 0.031667 | Topo I | Chemotherapy | 0.2810 | 0.03862 |