Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAMA-1 Neratinib
0.00031623
EGFR/HER2
RTK
 1.0219 0.00260
CAMA-1 Neratinib
0.001
EGFR/HER2
RTK
 0.9953 0.00028
CAMA-1 Neratinib
0.0031623
EGFR/HER2
RTK
 1.0126 0.00080
CAMA-1 Neratinib
0.01
EGFR/HER2
RTK
 0.9701 0.00223
CAMA-1 Neratinib
0.031623
EGFR/HER2
RTK
 0.9676 0.00776
CAMA-1 Neratinib
0.1
EGFR/HER2
RTK
 0.9956 -0.00089
CAMA-1 Neratinib
0.31623
EGFR/HER2
RTK
 0.9371 0.00691
CAMA-1 Neratinib
1.0
EGFR/HER2
RTK
 0.8236 0.00293
CAMA-1 Neratinib
3.1623
EGFR/HER2
RTK
 0.4493 0.03402
CAMA-1 Tivantinib
0.001
MET
RTK
 0.9944 0.00198
CAMA-1 Tivantinib
0.0031623
MET
RTK
 0.9782 -0.00333
CAMA-1 Tivantinib
0.01
MET
RTK
 1.0403 -0.00097
CAMA-1 Tivantinib
0.031623
MET
RTK
 0.9812 0.00295
CAMA-1 Tivantinib
0.1
MET
RTK
 0.9354 0.01054
CAMA-1 Tivantinib
0.31623
MET
RTK
 0.3882 0.19119
CAMA-1 Tivantinib
1.0
MET
RTK
 -0.2850 0.54568
CAMA-1 Tivantinib
3.1623
MET
RTK
 -0.5655 0.65245
CAMA-1 Tivantinib
10.0
MET
RTK
 -0.3540 0.45440
CAMA-1 Cediranib
0.001
VEGFR/cKIT
RTK
 0.9400 0.00343
CAMA-1 Cediranib
0.0031623
VEGFR/cKIT
RTK
 0.9554 0.00549
CAMA-1 Cediranib
0.01
VEGFR/cKIT
RTK
 1.0384 0.00221
CAMA-1 Cediranib
0.031623
VEGFR/cKIT
RTK
 1.0356 -0.00480
CAMA-1 Cediranib
0.1
VEGFR/cKIT
RTK
 1.0196 -0.00465
CAMA-1 Cediranib
0.31623
VEGFR/cKIT
RTK
 0.9926 -0.00416
CAMA-1 Cediranib
1.0
VEGFR/cKIT
RTK
 0.9506 -0.00764