Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAMA-1 AZD7762
0.01
CHK1/2
Cell cycle
 1.0162 -0.00250
CAMA-1 AZD7762
0.031623
CHK1/2
Cell cycle
 0.9360 -0.00127
CAMA-1 AZD7762
0.1
CHK1/2
Cell cycle
 0.6958 0.03756
CAMA-1 AZD7762
0.31623
CHK1/2
Cell cycle
 0.4526 0.07957
CAMA-1 AZD7762
1.0
CHK1/2
Cell cycle
 0.1438 0.15782
CAMA-1 AZD7762
3.1623
CHK1/2
Cell cycle
 -0.0865 0.19243
CAMA-1 AZD7762
10.0
CHK1/2
Cell cycle
 -0.0678 0.14249
CAMA-1 Volasertib
0.0001
PLK
Cell cycle
 0.9634 -0.00131
CAMA-1 Volasertib
0.00031623
PLK
Cell cycle
 0.9313 0.00167
CAMA-1 Volasertib
0.001
PLK
Cell cycle
 1.0189 0.00711
CAMA-1 Volasertib
0.0031623
PLK
Cell cycle
 0.9228 0.01916
CAMA-1 Volasertib
0.01
PLK
Cell cycle
 0.2699 0.17858
CAMA-1 Volasertib
0.031623
PLK
Cell cycle
 -0.2898 0.47100
CAMA-1 Volasertib
0.1
PLK
Cell cycle
 -0.3812 0.53477
CAMA-1 Volasertib
0.31623
PLK
Cell cycle
 -0.2965 0.48408
CAMA-1 Volasertib
1.0
PLK
Cell cycle
 -0.0983 0.15309
CAMA-1 Dinaciclib
0.0001
pan CDK
Cell cycle
 0.9611 -0.00160
CAMA-1 Dinaciclib
0.00031623
pan CDK
Cell cycle
 1.0393 -0.00207
CAMA-1 Dinaciclib
0.001
pan CDK
Cell cycle
 1.0151 0.00372
CAMA-1 Dinaciclib
0.0031623
pan CDK
Cell cycle
 0.9856 0.01091
CAMA-1 Dinaciclib
0.01
pan CDK
Cell cycle
 0.7116 0.05079
CAMA-1 Dinaciclib
0.031623
pan CDK
Cell cycle
 -0.0429 0.15298
CAMA-1 Dinaciclib
0.1
pan CDK
Cell cycle
 -0.3799 0.45483
CAMA-1 Dinaciclib
0.31623
pan CDK
Cell cycle
 -0.4166 0.50704
CAMA-1 Dinaciclib
1.0
pan CDK
Cell cycle
 -0.4849 0.55731