Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAMA-1 Cediranib
3.1623
VEGFR/cKIT
RTK
 0.8129 -0.00677
CAMA-1 Cediranib
10.0
VEGFR/cKIT
RTK
 -0.2923 0.41992
CAMA-1 Cabozantinib
0.001
VEGFR2/MET
RTK
 0.9447 -0.00001
CAMA-1 Cabozantinib
0.0031623
VEGFR2/MET
RTK
 0.9860 -0.00149
CAMA-1 Cabozantinib
0.01
VEGFR2/MET
RTK
 0.9955 0.00293
CAMA-1 Cabozantinib
0.031623
VEGFR2/MET
RTK
 1.0619 -0.00142
CAMA-1 Cabozantinib
0.1
VEGFR2/MET
RTK
 1.1109 0.00239
CAMA-1 Cabozantinib
0.31623
VEGFR2/MET
RTK
 1.0595 -0.00168
CAMA-1 Cabozantinib
1.0
VEGFR2/MET
RTK
 0.9992 0.00501
CAMA-1 Cabozantinib
3.1623
VEGFR2/MET
RTK
 1.0019 0.00408
CAMA-1 Cabozantinib
10.0
VEGFR2/MET
RTK
 0.2436 0.07088
HCC1428 Abemaciclib
0.001
CDK4/6
Cell cycle
 0.9431 -0.00488
HCC1428 Abemaciclib
0.0031623
CDK4/6
Cell cycle
 0.6836 0.00042
HCC1428 Abemaciclib
0.01
CDK4/6
Cell cycle
 0.4964 0.00835
HCC1428 Abemaciclib
0.031623
CDK4/6
Cell cycle
 0.3142 0.01325
HCC1428 Abemaciclib
0.1
CDK4/6
Cell cycle
 0.2268 0.01603
HCC1428 Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.2780 0.00351
HCC1428 Abemaciclib
1.0
CDK4/6
Cell cycle
 0.2301 0.00450
HCC1428 Abemaciclib
3.1623
CDK4/6
Cell cycle
 0.1876 0.02327
HCC1428 Abemaciclib
10.0
CDK4/6
Cell cycle
 0.0492 0.06729
HCC1428 Palbociclib
0.00031623
CDK4/6
Cell cycle
 1.0583 0.00026
HCC1428 Palbociclib
0.001
CDK4/6
Cell cycle
 1.0836 0.00088
HCC1428 Palbociclib
0.0031623
CDK4/6
Cell cycle
 1.1222 -0.00504
HCC1428 Palbociclib
0.01
CDK4/6
Cell cycle
 0.8798 0.00370
HCC1428 Palbociclib
0.031623
CDK4/6
Cell cycle
 0.7210 0.00098