Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAMA-1 Buparlisib
0.01
pan PI3K
PI3K/mTOR
 0.9003 0.00732
CAMA-1 Buparlisib
0.031623
pan PI3K
PI3K/mTOR
 0.9412 0.00311
CAMA-1 Buparlisib
0.1
pan PI3K
PI3K/mTOR
 0.9345 0.00111
CAMA-1 Buparlisib
0.31623
pan PI3K
PI3K/mTOR
 0.9384 0.00417
CAMA-1 Buparlisib
1.0
pan PI3K
PI3K/mTOR
 0.5109 0.09118
CAMA-1 Buparlisib
3.1623
pan PI3K
PI3K/mTOR
 -0.3082 0.46361
CAMA-1 Buparlisib
10.0
pan PI3K
PI3K/mTOR
 -0.4226 0.45985
CAMA-1 Pictilisib
0.001
pan PI3K
PI3K/mTOR
 0.9447 -0.00486
CAMA-1 Pictilisib
0.0031623
pan PI3K
PI3K/mTOR
 0.9351 -0.00247
CAMA-1 Pictilisib
0.01
pan PI3K
PI3K/mTOR
 0.9528 -0.00006
CAMA-1 Pictilisib
0.031623
pan PI3K
PI3K/mTOR
 1.0241 -0.00338
CAMA-1 Pictilisib
0.1
pan PI3K
PI3K/mTOR
 0.9225 0.00269
CAMA-1 Pictilisib
0.31623
pan PI3K
PI3K/mTOR
 0.8466 0.00385
CAMA-1 Pictilisib
1.0
pan PI3K
PI3K/mTOR
 0.6114 0.02964
CAMA-1 Pictilisib
3.1623
pan PI3K
PI3K/mTOR
 0.2578 0.08239
CAMA-1 Pictilisib
10.0
pan PI3K
PI3K/mTOR
 -0.2370 0.39310
CAMA-1 Ceritinib
0.001
ALK
RTK
 1.0023 0.00196
CAMA-1 Ceritinib
0.0031623
ALK
RTK
 1.0566 -0.00142
CAMA-1 Ceritinib
0.01
ALK
RTK
 1.0512 -0.00505
CAMA-1 Ceritinib
0.031623
ALK
RTK
 1.0219 0.00311
CAMA-1 Ceritinib
0.1
ALK
RTK
 1.0024 0.00070
CAMA-1 Ceritinib
0.31623
ALK
RTK
 0.9763 0.00050
CAMA-1 Ceritinib
1.0
ALK
RTK
 0.7201 0.01674
CAMA-1 Ceritinib
3.1623
ALK
RTK
 0.1350 0.09129
CAMA-1 Ceritinib
10.0
ALK
RTK
 -0.6988 0.76730