Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAL-85-1 Neratinib
0.1
EGFR/HER2
RTK
 0.2280 0.19666
CAL-85-1 Neratinib
0.31623
EGFR/HER2
RTK
 0.1036 0.28812
CAL-85-1 Neratinib
1.0
EGFR/HER2
RTK
 -0.0291 0.33812
CAL-85-1 Neratinib
3.1623
EGFR/HER2
RTK
 -0.3264 0.54060
CAL-85-1 Tivantinib
0.001
MET
RTK
 1.0697 -0.00911
CAL-85-1 Tivantinib
0.0031623
MET
RTK
 1.0107 -0.00363
CAL-85-1 Tivantinib
0.01
MET
RTK
 1.0404 0.00184
CAL-85-1 Tivantinib
0.031623
MET
RTK
 0.9083 0.02548
CAL-85-1 Tivantinib
0.1
MET
RTK
 0.7653 0.06755
CAL-85-1 Tivantinib
0.31623
MET
RTK
 0.2816 0.20294
CAL-85-1 Tivantinib
1.0
MET
RTK
 -0.2062 0.44890
CAL-85-1 Tivantinib
3.1623
MET
RTK
 -0.3263 0.55263
CAL-85-1 Tivantinib
10.0
MET
RTK
 -0.2984 0.49684
CAL-85-1 Cediranib
0.001
VEGFR/cKIT
RTK
 1.0205 0.00078
CAL-85-1 Cediranib
0.0031623
VEGFR/cKIT
RTK
 1.1164 -0.00108
CAL-85-1 Cediranib
0.01
VEGFR/cKIT
RTK
 1.0053 -0.00057
CAL-85-1 Cediranib
0.031623
VEGFR/cKIT
RTK
 1.0238 -0.01155
CAL-85-1 Cediranib
0.1
VEGFR/cKIT
RTK
 0.9781 -0.00005
CAL-85-1 Cediranib
0.31623
VEGFR/cKIT
RTK
 0.8835 0.01447
CAL-85-1 Cediranib
1.0
VEGFR/cKIT
RTK
 0.7867 0.04475
CAL-85-1 Cediranib
3.1623
VEGFR/cKIT
RTK
 0.3863 0.11888
CAL-85-1 Cediranib
10.0
VEGFR/cKIT
RTK
 -0.2379 0.29695
CAL-85-1 Cabozantinib
0.001
VEGFR2/MET
RTK
 0.9594 -0.00531
CAL-85-1 Cabozantinib
0.0031623
VEGFR2/MET
RTK
 0.9885 -0.00010
CAL-85-1 Cabozantinib
0.01
VEGFR2/MET
RTK
 0.9328 0.01462