Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1143 Everolimus
0.031623
mTOR1
PI3K/mTOR
 0.6954 0.02494
HCC1143 Everolimus
0.1
mTOR1
PI3K/mTOR
 0.6581 0.02582
HCC1143 Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.6602 0.02850
HCC1143 Everolimus
1.0
mTOR1
PI3K/mTOR
 0.6455 0.03451
HCC1143 Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.5952 0.04715
HCC1143 Everolimus
10.0
mTOR1
PI3K/mTOR
 0.5574 0.04421
HCC1143 INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 0.8872 0.00304
HCC1143 INK-128
0.001
mTORC1/2
PI3K/mTOR
 0.9268 0.00446
HCC1143 INK-128
0.0031623
mTORC1/2
PI3K/mTOR
 0.8971 -0.00408
HCC1143 INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.7439 0.01662
HCC1143 INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.5243 0.04150
HCC1143 INK-128
0.1
mTORC1/2
PI3K/mTOR
 0.3299 0.09368
HCC1143 INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.2063 0.11579
HCC1143 INK-128
1.0
mTORC1/2
PI3K/mTOR
 0.1183 0.13957
HCC1143 INK-128
3.1623
mTORC1/2
PI3K/mTOR
 0.0314 0.18360
HCC1143 PF-4708671
0.001
p70S6K
PI3K/mTOR
 0.9913 0.00007
HCC1143 PF-4708671
0.0031623
p70S6K
PI3K/mTOR
 0.9753 -0.00324
HCC1143 PF-4708671
0.01
p70S6K
PI3K/mTOR
 0.9987 0.00038
HCC1143 PF-4708671
0.031623
p70S6K
PI3K/mTOR
 0.9558 0.00077
HCC1143 PF-4708671
0.1
p70S6K
PI3K/mTOR
 1.0038 -0.00087
HCC1143 PF-4708671
0.31623
p70S6K
PI3K/mTOR
 0.9507 0.00070
HCC1143 PF-4708671
1.0
p70S6K
PI3K/mTOR
 0.9043 0.00256
HCC1143 PF-4708671
3.1623
p70S6K
PI3K/mTOR
 0.8347 0.01451
HCC1143 PF-4708671
10.0
p70S6K
PI3K/mTOR
 0.7394 0.02271
HCC1143 Buparlisib
0.001
pan PI3K
PI3K/mTOR
 0.9885 0.00427