Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1143 Buparlisib
0.0031623
pan PI3K
PI3K/mTOR
 0.9587 -0.00033
HCC1143 Buparlisib
0.01
pan PI3K
PI3K/mTOR
 0.9694 0.00201
HCC1143 Buparlisib
0.031623
pan PI3K
PI3K/mTOR
 0.9170 -0.00049
HCC1143 Buparlisib
0.1
pan PI3K
PI3K/mTOR
 0.8376 0.01161
HCC1143 Buparlisib
0.31623
pan PI3K
PI3K/mTOR
 0.7828 0.02382
HCC1143 Buparlisib
1.0
pan PI3K
PI3K/mTOR
 0.4130 0.10328
HCC1143 Buparlisib
3.1623
pan PI3K
PI3K/mTOR
 -0.2866 0.44490
HCC1143 Buparlisib
10.0
pan PI3K
PI3K/mTOR
 -0.4360 0.54948
HCC1143 Pictilisib
0.001
pan PI3K
PI3K/mTOR
 0.9892 -0.00175
HCC1143 Pictilisib
0.0031623
pan PI3K
PI3K/mTOR
 0.9256 0.00249
HCC1143 Pictilisib
0.01
pan PI3K
PI3K/mTOR
 0.9118 0.00558
HCC1143 Pictilisib
0.031623
pan PI3K
PI3K/mTOR
 0.8784 0.00589
HCC1143 Pictilisib
0.1
pan PI3K
PI3K/mTOR
 0.7385 0.01552
HCC1143 Pictilisib
0.31623
pan PI3K
PI3K/mTOR
 0.7266 0.02876
HCC1143 Pictilisib
1.0
pan PI3K
PI3K/mTOR
 0.5061 0.06152
HCC1143 Pictilisib
3.1623
pan PI3K
PI3K/mTOR
 0.3225 0.08622
HCC1143 Pictilisib
10.0
pan PI3K
PI3K/mTOR
 -0.1291 0.32075
HCC1143 Ceritinib
0.001
ALK
RTK
 0.9423 0.00058
HCC1143 Ceritinib
0.0031623
ALK
RTK
 0.9722 0.00658
HCC1143 Ceritinib
0.01
ALK
RTK
 1.0121 0.00091
HCC1143 Ceritinib
0.031623
ALK
RTK
 0.9284 0.00497
HCC1143 Ceritinib
0.1
ALK
RTK
 0.8931 0.01125
HCC1143 Ceritinib
0.31623
ALK
RTK
 0.8490 0.02506
HCC1143 Ceritinib
1.0
ALK
RTK
 0.6838 0.04877
HCC1143 Ceritinib
3.1623
ALK
RTK
 0.1228 0.12688