Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
A-375 Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 17737 603 1.0777 1.0016 0.0340 0.0383
A-375 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 1 11677 368 0.7113 0.6866 0.0315 0.0312
A-375 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 2 10880 316 0.6645 0.6866 0.0290 0.0312
A-375 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 3 11246 370 0.6841 0.6866 0.0329 0.0312
A-375 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 1 5745 285 0.3434 0.2974 0.0496 0.0491
A-375 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 2 5681 246 0.3419 0.2974 0.0433 0.0491
A-375 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 3 3476 189 0.2068 0.2974 0.0544 0.0491
A-375 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 1 7134 125 0.4409 0.4477 0.0175 0.0178
A-375 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 2 7416 121 0.4589 0.4477 0.0163 0.0178
A-375 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 3 7190 141 0.4434 0.4477 0.0196 0.0178
A-375 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 1 5860 137 0.3600 0.3831 0.0234 0.0229
A-375 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 2 6306 150 0.3872 0.3831 0.0238 0.0229
A-375 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 3 6531 140 0.4020 0.3831 0.0214 0.0229
A-375 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 1 5187 137 0.3177 0.2831 0.0264 0.0325
A-375 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 2 5169 175 0.3141 0.2831 0.0339 0.0325
A-375 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 3 3592 134 0.2175 0.2831 0.0373 0.0325
A-375 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 1 3804 246 0.2238 0.1826 0.0647 0.0764
A-375 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 2 3262 246 0.1897 0.1826 0.0754 0.0764
A-375 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 3 2345 209 0.1344 0.1826 0.0891 0.0764
A-375 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 1 3770 78 0.2322 0.2659 0.0207 0.0217
A-375 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 2 4429 94 0.2727 0.2659 0.0212 0.0217
A-375 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 3 4768 111 0.2929 0.2659 0.0233 0.0217
A-375 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 1 3156 117 0.1912 0.2100 0.0371 0.0374
A-375 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 2 3583 143 0.2164 0.2100 0.0399 0.0374
A-375 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 3 3667 129 0.2225 0.2100 0.0352 0.0374