Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A-375 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 1 | 3183 | 200 | 0.1876 | 0.1686 | 0.0628 | 0.0634 |
| A-375 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 2 | 3374 | 191 | 0.2002 | 0.1686 | 0.0566 | 0.0634 |
| A-375 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 3 | 2019 | 143 | 0.1180 | 0.1686 | 0.0708 | 0.0634 |
| A-375 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 1 | 1972 | 218 | 0.1103 | 0.1134 | 0.1105 | 0.1152 |
| A-375 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 2 | 2210 | 240 | 0.1239 | 0.1134 | 0.1086 | 0.1152 |
| A-375 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 3 | 1928 | 244 | 0.1059 | 0.1134 | 0.1266 | 0.1152 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 1 | 3294 | 114 | 0.2000 | 0.2091 | 0.0346 | 0.0362 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 2 | 3545 | 130 | 0.2148 | 0.2091 | 0.0367 | 0.0362 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 3 | 3510 | 131 | 0.2125 | 0.2091 | 0.0373 | 0.0362 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 1 | 2957 | 180 | 0.1747 | 0.1694 | 0.0609 | 0.0638 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 2 | 2861 | 198 | 0.1675 | 0.1694 | 0.0692 | 0.0638 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 3 | 2810 | 172 | 0.1659 | 0.1694 | 0.0612 | 0.0638 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 1 | 2570 | 251 | 0.1459 | 0.1321 | 0.0977 | 0.1085 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 2 | 2551 | 274 | 0.1432 | 0.1321 | 0.1074 | 0.1085 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 3 | 1935 | 233 | 0.1071 | 0.1321 | 0.1204 | 0.1085 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 1 | 1798 | 263 | 0.0966 | 0.0897 | 0.1463 | 0.1612 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 2 | 1834 | 275 | 0.0981 | 0.0897 | 0.1499 | 0.1612 |
| A-375 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 3 | 1458 | 273 | 0.0745 | 0.0897 | 0.1872 | 0.1612 |
| A-375 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 1 | 2723 | 183 | 0.1598 | 0.1658 | 0.0672 | 0.0732 |
| A-375 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 2 | 2962 | 234 | 0.1716 | 0.1658 | 0.0790 | 0.0732 |
| A-375 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 3 | 2847 | 209 | 0.1659 | 0.1658 | 0.0734 | 0.0732 |
| A-375 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 1 | 2256 | 271 | 0.1249 | 0.1123 | 0.1201 | 0.1236 |
| A-375 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 2 | 1959 | 237 | 0.1083 | 0.1123 | 0.1210 | 0.1236 |
| A-375 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 3 | 1897 | 246 | 0.1038 | 0.1123 | 0.1297 | 0.1236 |
| A-375 | Vemurafenib | JNK-IN-8 | 3.160 | 1.000 | uM | 72 | hr | 1 | 2301 | 378 | 0.1210 | 0.0981 | 0.1643 | 0.1764 |