Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MMAC-SF | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 1 | 1074 | 110 | 0.9466 | 0.6717 | 0.1024 | 0.0995 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 2 | 711 | 69 | 0.6304 | 0.6717 | 0.0970 | 0.0995 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 3 | 495 | 49 | 0.4380 | 0.6717 | 0.0990 | 0.0995 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 1 | 860 | 78 | 0.7679 | 0.6000 | 0.0907 | 0.1021 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 2 | 745 | 74 | 0.6589 | 0.6000 | 0.0993 | 0.1021 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 3 | 430 | 50 | 0.3732 | 0.6000 | 0.1163 | 0.1021 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 1 | 637 | 206 | 0.4232 | 0.5178 | 0.3234 | 0.3105 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 2 | 755 | 225 | 0.5205 | 0.5178 | 0.2980 | 0.3105 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 3 | 900 | 279 | 0.6098 | 0.5178 | 0.3100 | 0.3105 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 1 | 569 | 117 | 0.4439 | 0.5061 | 0.2056 | 0.1962 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 2 | 695 | 130 | 0.5548 | 0.5061 | 0.1871 | 0.1962 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 3 | 658 | 129 | 0.5195 | 0.5061 | 0.1960 | 0.1962 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 1 | 804 | 147 | 0.6452 | 0.5227 | 0.1828 | 0.1868 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 2 | 643 | 118 | 0.5155 | 0.5227 | 0.1835 | 0.1868 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 3 | 515 | 100 | 0.4075 | 0.5227 | 0.1942 | 0.1868 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 1 | 707 | 116 | 0.5804 | 0.4579 | 0.1641 | 0.1782 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 2 | 519 | 99 | 0.4124 | 0.4579 | 0.1908 | 0.1782 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 3 | 473 | 85 | 0.3810 | 0.4579 | 0.1797 | 0.1782 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 1 | 504 | 169 | 0.3290 | 0.3466 | 0.3353 | 0.3504 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 2 | 492 | 180 | 0.3064 | 0.3466 | 0.3659 | 0.3504 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 3 | 634 | 222 | 0.4046 | 0.3466 | 0.3502 | 0.3504 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 1 | 337 | 88 | 0.2445 | 0.2619 | 0.2611 | 0.2293 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 2 | 296 | 50 | 0.2416 | 0.2619 | 0.1689 | 0.2293 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 3 | 411 | 106 | 0.2995 | 0.2619 | 0.2579 | 0.2293 |
| MMAC-SF | Vemurafenib | JNK-IN-8 | 3.160 | 1.000 | uM | 72 | hr | 1 | 790 | 210 | 0.5696 | 0.3656 | 0.2658 | 0.2907 |