Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 1476 60 1.3905 1.3028 0.0407 0.0415
MMAC-SF Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 1 818 40 0.7640 0.6789 0.0489 0.0471
MMAC-SF Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 2 737 35 0.6894 0.6789 0.0475 0.0471
MMAC-SF Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 3 622 28 0.5833 0.6789 0.0450 0.0471
MMAC-SF Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 1 1095 43 1.0331 0.7915 0.0393 0.0491
MMAC-SF Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 2 854 49 0.7905 0.7915 0.0574 0.0491
MMAC-SF Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 3 591 30 0.5509 0.7915 0.0508 0.0491
MMAC-SF Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 1 721 33 0.6756 0.8036 0.0458 0.0497
MMAC-SF Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 2 913 53 0.8445 0.8036 0.0581 0.0497
MMAC-SF Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 3 950 43 0.8907 0.8036 0.0453 0.0497
MMAC-SF Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 1 734 32 0.6894 0.8164 0.0436 0.0519
MMAC-SF Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 2 901 55 0.8308 0.8164 0.0610 0.0519
MMAC-SF Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 3 997 51 0.9290 0.8164 0.0512 0.0519
MMAC-SF Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 1 985 40 0.9280 0.7182 0.0406 0.0494
MMAC-SF Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 2 755 33 0.7090 0.7182 0.0437 0.0494
MMAC-SF Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 3 563 36 0.5175 0.7182 0.0639 0.0494
MMAC-SF Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 1 933 49 0.8681 0.6959 0.0525 0.0496
MMAC-SF Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 2 757 37 0.7070 0.6959 0.0489 0.0496
MMAC-SF Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 3 548 26 0.5126 0.6959 0.0474 0.0496
MMAC-SF Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 1 682 97 0.5745 0.6805 0.1422 0.1572
MMAC-SF Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 2 871 154 0.7041 0.6805 0.1768 0.1572
MMAC-SF Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 3 917 140 0.7630 0.6805 0.1527 0.1572
MMAC-SF Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 1 714 97 0.6059 0.6759 0.1359 0.1363
MMAC-SF Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 2 808 122 0.6736 0.6759 0.1510 0.1363
MMAC-SF Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 3 868 106 0.7483 0.6759 0.1221 0.1363