Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib JNK-IN-8 3.160 1.000
uM
 72
hr
 2 462 141 0.3152 0.3656 0.3052 0.2907
MMAC-SF Vemurafenib JNK-IN-8 3.160 1.000
uM
 72
hr
 3 309 93 0.2121 0.3656 0.3010 0.2907
MMAC-SF Vemurafenib JNK-IN-8 3.160 3.160
uM
 72
hr
 1 348 58 0.2848 0.2478 0.1667 0.2217
MMAC-SF Vemurafenib JNK-IN-8 3.160 3.160
uM
 72
hr
 2 338 89 0.2445 0.2478 0.2633 0.2217
MMAC-SF Vemurafenib JNK-IN-8 3.160 3.160
uM
 72
hr
 3 285 67 0.2141 0.2478 0.2351 0.2217
MMAC-SF Vemurafenib PF562271 0.000 0.000
uM
 72
hr
 1 1026 46 0.9922 1.0000 0.0448 0.0473
MMAC-SF Vemurafenib PF562271 0.000 0.000
uM
 72
hr
 2 1114 46 1.0813 1.0000 0.0413 0.0473
MMAC-SF Vemurafenib PF562271 0.000 0.000
uM
 72
hr
 3 969 54 0.9264 1.0000 0.0557 0.0473
MMAC-SF Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 1 1207 52 1.1694 1.2926 0.0431 0.0509
MMAC-SF Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 2 1398 83 1.3314 1.2926 0.0594 0.0509
MMAC-SF Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 3 1432 72 1.3770 1.2926 0.0503 0.0509
MMAC-SF Vemurafenib PF562271 0.000 1.000
uM
 72
hr
 1 811 41 0.7796 0.6166 0.0506 0.0527
MMAC-SF Vemurafenib PF562271 0.000 1.000
uM
 72
hr
 2 555 40 0.5214 0.6166 0.0721 0.0527
MMAC-SF Vemurafenib PF562271 0.000 1.000
uM
 72
hr
 3 562 20 0.5488 0.6166 0.0356 0.0527
MMAC-SF Vemurafenib PF562271 0.000 3.160
uM
 72
hr
 1 792 31 0.7705 0.6021 0.0391 0.0426
MMAC-SF Vemurafenib PF562271 0.000 3.160
uM
 72
hr
 2 619 26 0.6004 0.6021 0.0420 0.0426
MMAC-SF Vemurafenib PF562271 0.000 3.160
uM
 72
hr
 3 451 21 0.4354 0.6021 0.0466 0.0426
MMAC-SF Vemurafenib PF562271 0.100 0.000
uM
 72
hr
 1 736 41 0.7037 0.8032 0.0557 0.0480
MMAC-SF Vemurafenib PF562271 0.100 0.000
uM
 72
hr
 2 894 41 0.8637 0.8032 0.0459 0.0480
MMAC-SF Vemurafenib PF562271 0.100 0.000
uM
 72
hr
 3 869 37 0.8424 0.8032 0.0426 0.0480
MMAC-SF Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 1 790 54 0.7452 0.9150 0.0684 0.0572
MMAC-SF Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 2 971 59 0.9234 0.9150 0.0608 0.0572
MMAC-SF Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 3 1110 47 1.0763 0.9150 0.0423 0.0572
MMAC-SF Vemurafenib PF562271 0.100 1.000
uM
 72
hr
 1 718 55 0.6713 0.5724 0.0766 0.0768
MMAC-SF Vemurafenib PF562271 0.100 1.000
uM
 72
hr
 2 618 52 0.5731 0.5724 0.0841 0.0768