Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 7798.077 | 1.0778 | 1.1070 | 1.4371 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 7798.077 | 0.9208 | 0.8883 | 1.4371 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 9157.034 | 1.0135 | 1.0254 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000945 | uM | 9157.034 | 0.9515 | 0.9083 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 9157.034 | 1.0014 | 1.0027 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 9157.034 | 1.0290 | 1.0548 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 9157.034 | 0.9627 | 0.9295 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 9157.034 | 1.0015 | 1.0029 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 9157.034 | 1.0179 | 1.0337 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 14.8 | uM | 9157.034 | 0.9737 | 0.9503 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 73.8 | uM | 9157.034 | 0.7892 | 0.5995 | 1.0593 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9158.121 | 1.0125 | 1.0234 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9158.121 | 1.1092 | 1.2035 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9158.121 | 0.9633 | 0.9313 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9158.121 | 1.0746 | 1.1392 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9158.121 | 1.0331 | 1.0619 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9158.121 | 1.0656 | 1.1225 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9158.121 | 0.9562 | 0.9179 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9158.121 | 1.0269 | 1.0502 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9158.121 | 0.6715 | 0.3780 | 1.0691 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9163.121 | 1.0634 | 1.3011 | 0.4382 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9163.121 | 1.0784 | 1.3757 | 0.4382 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9163.121 | 1.0129 | 1.0591 | 0.4382 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9163.121 | 1.0533 | 1.2515 | 0.4382 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9163.121 | 1.0646 | 1.3069 | 0.4382 |