Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7921.017 | 0.9708 | 0.9273 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7921.017 | 1.0085 | 1.0213 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7921.017 | 1.0128 | 1.0319 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7921.017 | 0.9990 | 0.9976 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7921.017 | 0.9507 | 0.8779 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7921.017 | 0.9935 | 0.9838 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7921.017 | 0.9020 | 0.7587 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7921.017 | 0.2838 | -0.5842 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7921.017 | 0.0166 | -0.9880 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 10146.049 | 1.1134 | 1.2578 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 10146.049 | 1.0648 | 1.1469 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 10146.049 | 1.2518 | 1.5770 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.16 | uM | 10146.049 | 1.0257 | 1.0582 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.8 | uM | 10146.049 | 1.0186 | 1.0419 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 4 | uM | 10146.049 | 1.1025 | 1.2328 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 10146.049 | 1.0425 | 1.0963 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 10146.049 | 1.0546 | 1.1237 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 10146.049 | 1.0417 | 1.0943 | 0.8861 | |
| SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9860.017 | 1.0786 | 1.0902 | 1.7158 | |
| SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9860.017 | 0.9908 | 0.9892 | 1.7158 | |
| SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9860.017 | 1.0039 | 1.0046 | 1.7158 | |
| SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9860.017 | 1.0116 | 1.0134 | 1.7158 | |
| SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9860.017 | 1.0225 | 1.0261 | 1.7158 | |
| SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9860.017 | 0.9519 | 0.9434 | 1.7158 | |
| SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9860.017 | 0.3031 | -0.0026 | 1.7158 |