Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13130.174 | 0.9606 | 0.8492 | 0.5126 | |
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13130.174 | 0.8473 | 0.4475 | 0.5126 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12690.174 | 0.9692 | 0.9745 | 2.4378 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12690.174 | 0.9728 | 0.9775 | 2.4378 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12690.174 | 0.9519 | 0.9600 | 2.4378 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12690.174 | 1.0472 | 1.0382 | 2.4378 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12690.174 | 0.8320 | 0.8547 | 2.4378 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12690.174 | 0.1738 | -0.0243 | 2.4378 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12690.174 | 0.2667 | 0.1630 | 2.4378 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12690.174 | 0.2264 | 0.0873 | 2.4378 | |
| BT-549 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12690.174 | 0.0888 | -0.2592 | 2.4378 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12647.174 | 0.9493 | 0.8919 | 0.9362 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12647.174 | 0.9959 | 0.9913 | 0.9362 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12647.174 | 0.9616 | 0.9182 | 0.9362 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12647.174 | 0.9557 | 0.9056 | 0.9362 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12647.174 | 0.8823 | 0.7495 | 0.9362 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12647.174 | 0.6333 | 0.2278 | 0.9362 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12647.174 | 0.9120 | 0.8126 | 0.9362 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12647.174 | 0.7782 | 0.5299 | 0.9362 | |
| CAMA-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12647.174 | 0.0072 | -0.9897 | 0.9362 | |
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13099.174 | 0.9401 | 0.8734 | 0.9441 | |
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13099.174 | 0.9834 | 0.9649 | 0.9441 | |
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13099.174 | 0.9781 | 0.9535 | 0.9441 | |
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13099.174 | 0.9923 | 0.9836 | 0.9441 | |
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13099.174 | 0.8154 | 0.6112 | 0.9441 |