Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9648.017 | 1.0151 | 1.0529 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9648.017 | 1.0143 | 1.0500 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9648.017 | 1.0379 | 1.1341 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9648.017 | 0.9951 | 0.9830 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9648.017 | 0.6543 | -0.0464 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9648.017 | 0.3736 | -0.6415 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9648.017 | 0.1102 | -0.9575 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10095.021 | 0.9761 | 0.9479 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10095.021 | 0.9786 | 0.9533 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10095.021 | 1.0431 | 1.0942 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10095.021 | 0.9949 | 0.9888 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10095.021 | 0.9724 | 0.9398 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10095.021 | 0.9559 | 0.9040 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10095.021 | 0.7177 | 0.3926 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10095.021 | 0.3790 | -0.3063 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10095.021 | 0.1679 | -0.7147 | 0.9164 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7897.035 | 0.9670 | 0.9215 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7897.035 | 0.9648 | 0.9162 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7897.035 | 1.0186 | 1.0445 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7897.035 | 0.9828 | 0.9589 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7897.035 | 1.0097 | 1.0231 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7897.035 | 1.0175 | 1.0420 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7897.035 | 0.9888 | 0.9733 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7897.035 | 0.6728 | 0.2463 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7897.035 | 0.1813 | -0.7395 | 0.8378 |