Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7862.017 | 0.9078 | 0.8586 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7862.017 | 0.8087 | 0.7028 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7862.017 | 0.6313 | 0.4115 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7862.017 | 0.0615 | -0.7582 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7862.017 | 0.0071 | -0.9530 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7863.017 | 1.0249 | 1.0253 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7863.017 | 1.0074 | 1.0076 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7863.017 | 1.0000 | 1.0000 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7863.017 | 1.0067 | 1.0068 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7863.017 | 0.9952 | 0.9951 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7863.017 | 0.8697 | 0.8622 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7863.017 | 0.5571 | 0.4832 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7863.017 | 0.3455 | 0.1619 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7863.017 | 0.8709 | 0.8636 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7864.017 | 0.9618 | 0.9536 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7864.017 | 1.0390 | 1.0468 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7864.017 | 0.9258 | 0.9090 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7864.017 | 0.9081 | 0.8869 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7864.017 | 0.9794 | 0.9751 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7864.017 | 0.7899 | 0.7345 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7864.017 | 0.6058 | 0.4778 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7864.017 | 0.0468 | -0.6853 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7864.017 | 0.0083 | -0.8895 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9511.021 | 1.0367 | 1.0543 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9511.021 | 0.9907 | 0.9861 | 1.3466 |