Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7824.017 | 0.4175 | 0.1852 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7824.017 | 0.3715 | 0.1053 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7824.017 | 0.2127 | -0.2086 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7825.017 | 0.9599 | 0.9611 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7825.017 | 1.0002 | 1.0002 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7825.017 | 1.0674 | 1.0635 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7825.017 | 0.9761 | 0.9769 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7825.017 | 0.9621 | 0.9633 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7825.017 | 0.9160 | 0.9176 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7825.017 | 0.5510 | 0.5028 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7825.017 | 0.5221 | 0.4646 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7825.017 | 0.3639 | 0.2318 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9347.017 | 1.0357 | 1.0436 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9347.017 | 1.0270 | 1.0331 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9347.017 | 1.0474 | 1.0579 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9347.017 | 0.9923 | 0.9905 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9347.017 | 0.9831 | 0.9792 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9347.017 | 0.9990 | 0.9988 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9347.017 | 0.7880 | 0.7272 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9347.017 | 0.5969 | 0.4558 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9347.017 | 0.2443 | -0.1599 | 1.6249 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7829.017 | 1.0386 | 1.0391 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7829.017 | 0.9717 | 0.9709 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7829.017 | 1.0154 | 1.0157 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7829.017 | 0.9893 | 0.9891 | 1.9566 |