Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 9158.049 | 0.9958 | 0.9795 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9163.03 | 1.0464 | 1.2739 | 0.3535 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9163.03 | 0.9835 | 0.9080 | 0.3535 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9163.03 | 1.1024 | 1.6348 | 0.3535 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9163.03 | 1.0161 | 1.0923 | 0.3535 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9163.03 | 1.0506 | 1.2994 | 0.3535 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9163.03 | 1.0243 | 1.1408 | 0.3535 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9163.03 | 1.0354 | 1.2065 | 0.3535 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9163.03 | 0.4566 | -0.7822 | 0.3535 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9163.03 | 0.0593 | -0.9993 | 0.3535 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7801.035 | 1.0004 | 1.0015 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7801.035 | 0.9900 | 0.9633 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7801.035 | 1.0008 | 1.0028 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7801.035 | 0.9548 | 0.8366 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7801.035 | 0.9934 | 0.9756 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7801.035 | 1.0784 | 1.2984 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7801.035 | 0.8971 | 0.6372 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7801.035 | 0.4835 | -0.4757 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7801.035 | 0.2979 | -0.7852 | 0.5427 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 9186.049 | 1.1221 | 1.3621 | 0.6923 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 9186.049 | 1.0222 | 1.0644 | 0.6923 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 9186.049 | 1.0414 | 1.1207 | 0.6923 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.16 | uM | 9186.049 | 0.9789 | 0.9394 | 0.6923 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.8 | uM | 9186.049 | 1.0818 | 1.2405 | 0.6923 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 4 | uM | 9186.049 | 1.0094 | 1.0273 | 0.6923 |