Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Chloroquine | 0.000851 | uM | 12617.177 | 0.9271 | 0.9119 | 1.6822 | |||
| HCC38 | TNBC | Basal B | Chloroquine | 0.00426 | uM | 12617.177 | 0.9711 | 0.9654 | 1.6822 | |||
| HCC38 | TNBC | Basal B | Chloroquine | 0.0213 | uM | 12617.177 | 0.9838 | 0.9807 | 1.6822 | |||
| HCC38 | TNBC | Basal B | Chloroquine | 0.106 | uM | 12617.177 | 0.9848 | 0.9819 | 1.6822 | |||
| HCC38 | TNBC | Basal B | Chloroquine | 0.532 | uM | 12617.177 | 0.9505 | 0.9405 | 1.6822 | |||
| HCC38 | TNBC | Basal B | Chloroquine | 2.66 | uM | 12617.177 | 0.9667 | 0.9602 | 1.6822 | |||
| HCC38 | TNBC | Basal B | Chloroquine | 13.3 | uM | 12617.177 | 0.6868 | 0.5996 | 1.6822 | |||
| HCC38 | TNBC | Basal B | Chloroquine | 66.5 | uM | 12617.177 | 0.2267 | -0.1723 | 1.6822 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 0.00017 | uM | 12622.177 | 1.0126 | 1.0099 | 2.5433 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 0.000851 | uM | 12622.177 | 0.9962 | 0.9970 | 2.5433 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 0.00426 | uM | 12622.177 | 0.9918 | 0.9935 | 2.5433 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 0.0213 | uM | 12622.177 | 0.9793 | 0.9836 | 2.5433 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 0.106 | uM | 12622.177 | 0.9680 | 0.9746 | 2.5433 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 0.532 | uM | 12622.177 | 0.9857 | 0.9887 | 2.5433 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 2.66 | uM | 12622.177 | 0.7632 | 0.7984 | 2.5433 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 13.3 | uM | 12622.177 | 0.1119 | -0.1547 | 2.5433 | |||
| Hs 578T | TNBC | Basal B | Chloroquine | 66.5 | uM | 12622.177 | 0.0104 | -0.6678 | 2.5433 | |||
| LY2 | HR+ | Luminal | Chloroquine | 0.00017 | uM | 12627.177 | 0.9770 | 0.9642 | 1.2910 | |||
| LY2 | HR+ | Luminal | Chloroquine | 0.000851 | uM | 12627.177 | 0.9774 | 0.9649 | 1.2910 | |||
| LY2 | HR+ | Luminal | Chloroquine | 0.00426 | uM | 12627.177 | 1.0056 | 1.0086 | 1.2910 | |||
| LY2 | HR+ | Luminal | Chloroquine | 0.0213 | uM | 12627.177 | 0.9562 | 0.9318 | 1.2910 | |||
| LY2 | HR+ | Luminal | Chloroquine | 0.106 | uM | 12627.177 | 0.9963 | 0.9942 | 1.2910 | |||
| LY2 | HR+ | Luminal | Chloroquine | 0.532 | uM | 12627.177 | 0.9587 | 0.9357 | 1.2910 | |||
| LY2 | HR+ | Luminal | Chloroquine | 2.66 | uM | 12627.177 | 0.9391 | 0.9050 | 1.2910 | |||
| LY2 | HR+ | Luminal | Chloroquine | 13.3 | uM | 12627.177 | 0.4475 | 0.0729 | 1.2910 |