Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 10151.034 | 0.8398 | 0.1641 | 0.3226 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 10151.034 | 0.8602 | 0.2537 | 0.3226 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 10151.034 | 0.8504 | 0.2103 | 0.3226 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 10151.034 | 0.8658 | 0.2796 | 0.3226 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 10151.034 | 0.6138 | -0.5595 | 0.3226 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 10151.034 | 0.0277 | -1.0000 | 0.3226 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10267.026 | 1.1984 | 2.5690 | 0.3125 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 10267.026 | 1.1317 | 1.9715 | 0.3125 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 10267.026 | 1.1812 | 2.4076 | 0.3125 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 10267.026 | 0.8248 | 0.0796 | 0.3125 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 10267.026 | 0.9363 | 0.6199 | 0.3125 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 10267.026 | 0.9039 | 0.4476 | 0.3125 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 10267.026 | 0.8689 | 0.2755 | 0.3125 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 10267.026 | 0.7514 | -0.1986 | 0.3125 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 10267.026 | 0.0785 | -0.9994 | 0.3125 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9045.018 | 1.1817 | 1.3341 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9045.018 | 0.8890 | 0.7938 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9045.018 | 1.1714 | 1.3152 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9045.018 | 0.8656 | 0.7499 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9045.018 | 0.9633 | 0.9321 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9045.018 | 0.8041 | 0.6346 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9045.018 | 0.7715 | 0.5732 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9045.018 | 0.8117 | 0.6489 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9045.018 | 0.3581 | -0.2268 | 1.0807 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9933.034 | 1.1275 | 1.4768 | 0.5612 |