Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Chloroquine | 0.0213 | uM | 12612.177 | 0.9591 | 0.8435 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | Chloroquine | 0.106 | uM | 12612.177 | 0.9227 | 0.7093 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | Chloroquine | 0.532 | uM | 12612.177 | 0.9269 | 0.7242 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | Chloroquine | 2.66 | uM | 12612.177 | 0.8836 | 0.5705 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | Chloroquine | 13.3 | uM | 12612.177 | 0.7761 | 0.2191 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | Chloroquine | 66.5 | uM | 12612.177 | 0.3029 | -0.8059 | 0.5119 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 0.00017 | uM | 13038.177 | 1.2787 | 1.6157 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 0.000851 | uM | 13038.177 | 1.1529 | 1.3360 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 0.00426 | uM | 13038.177 | 1.1304 | 1.2864 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 0.0213 | uM | 13038.177 | 1.1056 | 1.2315 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 0.106 | uM | 13038.177 | 1.4038 | 1.8962 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 0.532 | uM | 13038.177 | 1.2218 | 1.4888 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 2.66 | uM | 13038.177 | 1.0953 | 1.2090 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 13.3 | uM | 13038.177 | 0.5924 | 0.1294 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | Chloroquine | 66.5 | uM | 13038.177 | 0.0009 | -0.9991 | 0.9161 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 0.00017 | uM | 12702.177 | 0.9898 | 0.9870 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 0.000851 | uM | 12702.177 | 0.9978 | 0.9972 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 0.00426 | uM | 12702.177 | 1.0014 | 1.0018 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 0.0213 | uM | 12702.177 | 0.9729 | 0.9654 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 0.106 | uM | 12702.177 | 1.0315 | 1.0399 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 0.532 | uM | 12702.177 | 1.0194 | 1.0245 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 2.66 | uM | 12702.177 | 0.8788 | 0.8423 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 13.3 | uM | 12702.177 | 0.2992 | -0.0713 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | Chloroquine | 66.5 | uM | 12702.177 | 0.0741 | -0.6177 | 1.5730 | |||
| HCC38 | TNBC | Basal B | Chloroquine | 0.00017 | uM | 12617.177 | 0.9490 | 0.9387 | 1.6822 |