Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Chloroquine | 0.532 | uM | 13125.177 | 0.8827 | 0.7409 | 0.8991 | |||
| BT-474 | HER2amp | Luminal | Chloroquine | 2.66 | uM | 13125.177 | 0.9685 | 0.9300 | 0.8991 | |||
| BT-474 | HER2amp | Luminal | Chloroquine | 13.3 | uM | 13125.177 | 0.8854 | 0.7467 | 0.8991 | |||
| BT-474 | HER2amp | Luminal | Chloroquine | 66.5 | uM | 13125.177 | 0.0112 | -0.9865 | 0.8991 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 0.00017 | uM | 12647.177 | 0.9936 | 0.9877 | 1.0387 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 0.000851 | uM | 12647.177 | 0.8794 | 0.7673 | 1.0387 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 0.00426 | uM | 12647.177 | 0.9320 | 0.8689 | 1.0387 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 0.0213 | uM | 12647.177 | 0.9857 | 0.9725 | 1.0387 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 0.106 | uM | 12647.177 | 0.9643 | 0.9312 | 1.0387 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 0.532 | uM | 12647.177 | 0.9182 | 0.8422 | 1.0387 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 2.66 | uM | 12647.177 | 0.9521 | 0.9077 | 1.0387 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 13.3 | uM | 12647.177 | 0.7015 | 0.4217 | 1.0387 | |||
| CAMA-1 | HR+ | Luminal | Chloroquine | 66.5 | uM | 12647.177 | 0.0106 | -0.9748 | 1.0387 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 0.00017 | uM | 13099.177 | 0.8155 | 0.5194 | 0.7419 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 0.000851 | uM | 13099.177 | 0.9804 | 0.9474 | 0.7419 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 0.00426 | uM | 13099.177 | 0.6389 | 0.0934 | 0.7419 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 0.0213 | uM | 13099.177 | 0.1972 | -0.7758 | 0.7419 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 0.106 | uM | 13099.177 | 1.2856 | 1.8060 | 0.7419 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 0.532 | uM | 13099.177 | 1.0480 | 1.1305 | 0.7419 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 2.66 | uM | 13099.177 | 0.8121 | 0.5108 | 0.7419 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 13.3 | uM | 13099.177 | 0.4694 | -0.2783 | 0.7419 | |||
| HCC1143 | TNBC | Basal A | Chloroquine | 66.5 | uM | 13099.177 | 0.0004 | -0.9999 | 0.7419 | |||
| HCC1419 | HER2amp | Luminal | Chloroquine | 0.00017 | uM | 12612.177 | 0.9698 | 0.8837 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | Chloroquine | 0.000851 | uM | 12612.177 | 0.9337 | 0.7493 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | Chloroquine | 0.00426 | uM | 12612.177 | 0.9348 | 0.7531 | 0.5119 |