Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 9186.049 | 1.0129 | 1.0374 | 0.6923 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 9186.049 | 1.0827 | 1.2433 | 0.6923 | |
| BT-483 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 9186.049 | 1.1181 | 1.3500 | 0.6923 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7803.017 | 1.0361 | 1.0241 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7803.017 | 0.9882 | 0.9920 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7803.017 | 0.9866 | 0.9909 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7803.017 | 0.9680 | 0.9781 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7803.017 | 0.9099 | 0.9371 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7803.017 | 0.6505 | 0.7293 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7803.017 | 0.1160 | -0.0347 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7803.017 | 0.0073 | -0.6212 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7803.017 | 0.0030 | -0.7208 | 2.9572 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7804.017 | 1.0090 | 1.0069 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7804.017 | 0.9875 | 0.9903 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7804.017 | 0.9769 | 0.9821 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7804.017 | 0.9808 | 0.9851 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7804.017 | 0.9876 | 0.9904 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7804.017 | 0.7817 | 0.8190 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7804.017 | 0.3658 | 0.3578 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7804.017 | 0.0096 | -0.6655 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7804.017 | 0.0066 | -0.7110 | 2.5963 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10261.131 | 1.0398 | 1.0328 | 2.3992 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10261.131 | 0.9830 | 0.9857 | 2.3992 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10261.131 | 1.0042 | 1.0035 | 2.3992 | |
| BT-549 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10261.131 | 0.9640 | 0.9697 | 2.3992 |