Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7798.017 | 0.9540 | 0.9346 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7798.017 | 1.0024 | 1.0034 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7798.017 | 0.9521 | 0.9319 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7798.017 | 1.0367 | 1.0515 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7798.017 | 1.0571 | 1.0800 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7798.017 | 0.9798 | 0.9713 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7798.017 | 0.5804 | 0.3621 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7798.017 | 0.1911 | -0.3785 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9157.021 | 1.0064 | 1.0126 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9157.021 | 0.9520 | 0.9050 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9157.021 | 1.0288 | 1.0570 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9157.021 | 0.9973 | 0.9946 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9157.021 | 0.9415 | 0.8842 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9157.021 | 1.0223 | 1.0441 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9157.021 | 0.9419 | 0.8850 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9157.021 | 0.4297 | -0.1325 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9157.021 | 0.1933 | -0.6064 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 9158.049 | 0.9037 | 0.5604 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 9158.049 | 1.2004 | 2.1287 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 9158.049 | 1.0263 | 1.1314 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.16 | uM | 9158.049 | 1.0660 | 1.3393 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.8 | uM | 9158.049 | 0.9775 | 0.8913 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 4 | uM | 9158.049 | 1.0847 | 1.4411 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 9158.049 | 0.9096 | 0.5857 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 9158.049 | 0.9182 | 0.6224 | 0.4082 |