Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10124.021 | 0.2984 | 0.0839 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10124.021 | 0.1461 | -0.2450 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10124.021 | 0.2204 | -0.0703 | 1.9744 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10147.021 | 0.9755 | 0.9774 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10147.021 | 0.9717 | 0.9739 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10147.021 | 0.9699 | 0.9722 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10147.021 | 0.8369 | 0.8435 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10147.021 | 0.9699 | 0.9722 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10147.021 | 0.7976 | 0.8034 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10147.021 | 0.6333 | 0.6228 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10147.021 | 0.0815 | -0.3649 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10147.021 | 0.0099 | -0.7574 | 2.1856 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7861.017 | 1.0256 | 1.0282 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7861.017 | 1.0356 | 1.0391 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7861.017 | 1.0367 | 1.0403 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7861.017 | 0.8751 | 0.8576 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7861.017 | 0.9727 | 0.9696 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7861.017 | 0.9096 | 0.8978 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7861.017 | 0.4072 | 0.2164 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7861.017 | 0.1229 | -0.3732 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7861.017 | 0.0958 | -0.4540 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7862.017 | 0.9656 | 0.9476 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7862.017 | 0.9902 | 0.9851 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7862.017 | 0.9246 | 0.8846 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7862.017 | 0.9380 | 0.9054 | 1.3198 |