Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9511.021 | 1.0797 | 1.1171 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9511.021 | 0.9740 | 0.9613 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9511.021 | 0.9486 | 0.9232 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9511.021 | 0.9582 | 0.9376 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9511.021 | 0.8764 | 0.8134 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9511.021 | 0.1326 | -0.5539 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9511.021 | 0.0385 | -0.8220 | 1.3466 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7865.017 | 0.7780 | 0.7541 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7865.017 | 0.8073 | 0.7884 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7865.017 | 0.8123 | 0.7941 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7865.017 | 0.7975 | 0.7769 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7865.017 | 1.0183 | 1.0191 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7865.017 | 0.9561 | 0.9536 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7865.017 | 0.6565 | 0.6052 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7865.017 | 0.0761 | -0.4793 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7865.017 | 0.0007 | -0.9549 | 1.9138 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9536.017 | 1.0028 | 1.0039 | 1.4526 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9536.017 | 0.9764 | 0.9674 | 1.4526 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9536.017 | 0.9957 | 0.9941 | 1.4526 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9536.017 | 0.9867 | 0.9816 | 1.4526 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9536.017 | 1.0087 | 1.0119 | 1.4526 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9536.017 | 0.9096 | 0.8737 | 1.4526 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9536.017 | 0.6931 | 0.5540 | 1.4526 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9536.017 | 0.0861 | -0.6302 | 1.4526 | |
| LY2 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9536.017 | 0.0112 | -0.9093 | 1.4526 |