CPT-11 - Small Molecule (ID:10246-101)
| HMS LINCS ID: |
10246-101
|
| Name: | CPT-11 |
| Alternative Names: | Irinotecan |
| LINCS ID: | LSM-2167 |
| PubChem CID: | 60838 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 586.28 |
| InChi: | InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3/t33-/m0/s1 |
| InChi Key: | UWKQSNNFCGGAFS-XIFFEERXSA-N |
| SMILES: | CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ACHE | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | TOP1 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MMP1, SLC47A1 |
Batch Information for HMSL10246-101-1:
| HMS LINCS Batch ID: | 10246-101-1 |
| Provider: | J Park (UCSF) |
| Provider Batch ID: | |
| Salt: | 101 |
| Molecular Formula: | |
| Molecular Weight: | |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2012-11-14 |
| Most Recent Update: | 2016-12-02 |
(Kd <100 nM)