Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13558.174 | 0.4857 | -0.4369 | 0.5699 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13558.174 | 0.8563 | 0.5232 | 0.5699 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13558.174 | 0.8276 | 0.4349 | 0.5699 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13558.174 | 0.8401 | 0.4732 | 0.5699 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12959.174 | 0.9451 | 0.7871 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12959.174 | 0.9418 | 0.7747 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12959.174 | 0.9630 | 0.8552 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12959.174 | 0.9438 | 0.7821 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12959.174 | 0.9540 | 0.8208 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12959.174 | 0.9382 | 0.7613 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12959.174 | 0.9617 | 0.8502 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12959.174 | 0.8335 | 0.3915 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12959.174 | 0.5107 | -0.4756 | 0.5020 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13587.174 | 0.9724 | 0.9212 | 0.6955 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13587.174 | 0.9714 | 0.9182 | 0.6955 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13587.174 | 0.9679 | 0.9082 | 0.6955 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13587.174 | 0.9322 | 0.8080 | 0.6955 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13587.174 | 0.9687 | 0.9105 | 0.6955 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13587.174 | 0.9415 | 0.8339 | 0.6955 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13587.174 | 0.9844 | 0.9552 | 0.6955 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13587.174 | 0.7860 | 0.4148 | 0.6955 | |
| MDA-MB-415 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13587.174 | 0.0232 | -0.9911 | 0.6955 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12964.174 | 0.9559 | 0.8889 | 0.7885 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12964.174 | 0.9927 | 0.9814 | 0.7885 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12964.174 | 0.9829 | 0.9567 | 0.7885 |