Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7809.017 | 0.7737 | 0.7286 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7809.017 | 0.5703 | 0.4534 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7809.017 | 0.1353 | -0.3586 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7809.017 | 0.1215 | -0.3966 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7809.017 | 0.0584 | -0.6023 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7809.017 | 0.0011 | -0.9582 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7810.017 | 1.0454 | 1.1013 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7810.017 | 1.0245 | 1.0545 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7810.017 | 1.0287 | 1.0641 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7810.017 | 1.0360 | 1.0804 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7810.017 | 0.8746 | 0.7229 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7810.017 | 0.1537 | -0.7512 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7810.017 | 0.1154 | -0.8192 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7810.017 | 0.0821 | -0.8761 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7810.017 | 0.0002 | -0.9998 | 0.8986 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7811.017 | 0.9856 | 0.9212 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7811.017 | 1.0092 | 1.0516 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7811.017 | 0.9855 | 0.9205 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7811.017 | 0.8646 | 0.3359 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7811.017 | 0.8605 | 0.3182 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7811.017 | 0.0654 | -0.9990 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7811.017 | 0.0322 | -0.9999 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7811.017 | 0.0161 | -1.0000 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7811.017 | 0.0053 | -1.0000 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7812.017 | 1.0373 | 1.0656 | 1.1362 |