Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12964.174 | 1.0083 | 1.0210 | 0.7885 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12964.174 | 0.7087 | 0.2924 | 0.7885 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12964.174 | 0.4676 | -0.2373 | 0.7885 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12964.174 | 0.7501 | 0.3889 | 0.7885 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12964.174 | 0.5540 | -0.0544 | 0.7885 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12964.174 | 0.7526 | 0.3947 | 0.7885 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13562.174 | 1.0182 | 1.0505 | 0.7219 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13562.174 | 0.9816 | 0.9491 | 0.7219 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13562.174 | 1.0263 | 1.0733 | 0.7219 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13562.174 | 1.0095 | 1.0262 | 0.7219 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13562.174 | 0.5384 | -0.1518 | 0.7219 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13562.174 | 0.4369 | -0.3649 | 0.7219 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13562.174 | 0.7131 | 0.2521 | 0.7219 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13562.174 | 0.6954 | 0.2092 | 0.7219 | |
| MDA-MB-453 | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13562.174 | 0.6836 | 0.1809 | 0.7219 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12667.174 | 1.0245 | 1.0606 | 0.8129 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12667.174 | 1.0232 | 1.0573 | 0.8129 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12667.174 | 1.0484 | 1.1197 | 0.8129 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12667.174 | 1.0464 | 1.1146 | 0.8129 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12667.174 | 0.9151 | 0.7932 | 0.8129 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12667.174 | 0.7857 | 0.4866 | 0.8129 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12667.174 | 0.9434 | 0.8615 | 0.8129 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12667.174 | 0.9291 | 0.8270 | 0.8129 | |
| MX1 | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12667.174 | 0.3474 | -0.4553 | 0.8129 | |
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12999.174 | 1.0138 | 1.0332 | 0.8315 |