Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12999.174 | 1.0301 | 1.0727 | 0.8315 | |
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12999.174 | 1.0079 | 1.0191 | 0.8315 | |
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12999.174 | 1.0000 | 1.0000 | 0.8315 | |
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12999.174 | 0.7836 | 0.4917 | 0.8315 | |
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12999.174 | 0.2121 | -0.6903 | 0.8315 | |
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12999.174 | 0.4986 | -0.1341 | 0.8315 | |
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12999.174 | 0.8184 | 0.5717 | 0.8315 | |
| SK-BR-3 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12999.174 | 0.0682 | -0.9208 | 0.8315 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13123.174 | 0.9368 | 0.8785 | 1.0408 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13123.174 | 1.1006 | 1.1929 | 1.0408 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13123.174 | 0.9524 | 0.9085 | 1.0408 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13123.174 | 0.9297 | 0.8648 | 1.0408 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13123.174 | 0.9668 | 0.9361 | 1.0408 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13123.174 | 0.7361 | 0.4899 | 1.0408 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13123.174 | 0.9825 | 0.9663 | 1.0408 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13123.174 | 0.4491 | -0.0732 | 1.0408 | |
| SUM149PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13123.174 | 0.9495 | 0.9028 | 1.0408 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13004.174 | 0.8261 | 0.8867 | 3.2757 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13004.174 | 0.8984 | 0.9356 | 3.2757 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13004.174 | 0.8757 | 0.9206 | 3.2757 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13004.174 | 0.8468 | 0.9010 | 3.2757 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13004.174 | 0.6851 | 0.7819 | 3.2757 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13004.174 | 0.3129 | 0.4028 | 3.2757 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13004.174 | 0.6262 | 0.7337 | 3.2757 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13004.174 | 0.0561 | -0.1701 | 3.2757 |