Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7814.017 | 0.0004 | -0.9999 | 0.8254 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7816.017 | 0.9640 | 0.9413 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7816.017 | 0.9624 | 0.9388 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7816.017 | 1.0022 | 1.0035 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7816.017 | 0.9617 | 0.9376 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7816.017 | 0.7958 | 0.6616 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7816.017 | 0.8426 | 0.7404 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7816.017 | 0.5360 | 0.2055 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7816.017 | 0.7823 | 0.6386 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7816.017 | 0.9855 | 0.9764 | 1.2318 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7820.017 | 0.9196 | 0.7718 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7820.017 | 0.9169 | 0.7642 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7820.017 | 1.0221 | 1.0644 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7820.017 | 0.9974 | 0.9926 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7820.017 | 0.9656 | 0.9012 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7820.017 | 0.5258 | -0.2105 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7820.017 | 0.3564 | -0.5502 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7820.017 | 0.2322 | -0.7578 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7820.017 | 0.0013 | -0.9999 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7821.017 | 1.1071 | 1.6157 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7821.017 | 1.0034 | 1.0177 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7821.017 | 1.0331 | 1.1792 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7821.017 | 1.0610 | 1.3381 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7821.017 | 1.0283 | 1.1528 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7821.017 | 0.4993 | -0.6797 | 0.3792 |