Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7812.017 | 0.8850 | 0.7960 | 1.1362 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7812.017 | 1.0485 | 1.0851 | 1.1362 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7812.017 | 0.9497 | 0.9111 | 1.1362 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7812.017 | 1.0797 | 1.1397 | 1.1362 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7812.017 | 0.1165 | -0.6984 | 1.1362 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7812.017 | 0.0462 | -0.8664 | 1.1362 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7812.017 | 0.0268 | -0.9174 | 1.1362 | |
| HCC1187 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7812.017 | 0.0002 | -0.9987 | 1.1362 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7813.017 | 1.0272 | 1.0627 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7813.017 | 0.8980 | 0.7669 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7813.017 | 1.0762 | 1.1765 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7813.017 | 1.0046 | 1.0107 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7813.017 | 0.9775 | 0.9482 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7813.017 | 0.7177 | 0.3651 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7813.017 | 0.2001 | -0.6863 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7813.017 | 0.1524 | -0.7707 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7813.017 | 0.0020 | -0.9985 | 0.8685 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7814.017 | 1.0357 | 1.0868 | 0.8254 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7814.017 | 1.0249 | 1.0606 | 0.8254 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7814.017 | 0.8345 | 0.6063 | 0.8254 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7814.017 | 0.9737 | 0.9364 | 0.8254 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7814.017 | 0.5921 | 0.0599 | 0.8254 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7814.017 | 0.4455 | -0.2491 | 0.8254 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7814.017 | 0.1255 | -0.8382 | 0.8254 | |
| HCC1395 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7814.017 | 0.0993 | -0.8781 | 0.8254 |