Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
AU565
HER2amp
Luminal
Everolimus
MTOR
MTOR
2.67
uM
10880.156
0.5612 0.3707 1.5288
AU565
HER2amp
Luminal
Everolimus
MTOR
MTOR
13.3
uM
10880.156
0.5170 0.2991 1.5288
AU565
HER2amp
Luminal
Everolimus
MTOR
MTOR
66.7
uM
10880.156
0.0138 -0.8788 1.5288
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
0.000171
uM
11854.156
1.0804 1.1469 1.0916
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
0.000853
uM
11854.156
1.0546 1.0998 1.0916
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
0.00427
uM
11854.156
1.0437 1.0800 1.0916
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
0.0213
uM
11854.156
0.9509 0.9098 1.0916
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
0.107
uM
11854.156
0.6788 0.4025 1.0916
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
0.533
uM
11854.156
0.7111 0.4634 1.0916
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
2.67
uM
11854.156
0.7384 0.5149 1.0916
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
13.3
uM
11854.156
0.6902 0.4241 1.0916
BT-20
TNBC
Basal A
Everolimus
MTOR
MTOR
66.7
uM
11854.156
0.3313 -0.2730 1.0916
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.000171
uM
12056.164
0.9441 0.8804 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.000853
uM
12056.164
0.8978 0.7817 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.00427
uM
12056.164
0.8519 0.6842 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.0213
uM
12056.164
0.7247 0.4162 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.107
uM
12056.164
0.6068 0.1707 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.533
uM
12056.164
0.6495 0.2592 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
2.67
uM
12056.164
0.6320 0.2228 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
13.3
uM
12056.164
0.5796 0.1146 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
66.7
uM
12056.164
0.2994 -0.4510 0.9328
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.000171
uM
12178.164
1.0391 1.1401 0.5660
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.000853
uM
12178.164
1.0218 1.0776 0.5660
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.00427
uM
12178.164
0.8541 0.5136 0.5660
BT-474
HER2amp
Luminal
Everolimus
MTOR
MTOR
0.0213
uM
12178.164
0.8144 0.3915 0.5660