Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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AU565 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 10880.156 | 0.5612 | 0.3707 | 1.5288 | |
AU565 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 10880.156 | 0.5170 | 0.2991 | 1.5288 | |
AU565 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 10880.156 | 0.0138 | -0.8788 | 1.5288 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.000171 | uM | 11854.156 | 1.0804 | 1.1469 | 1.0916 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.000853 | uM | 11854.156 | 1.0546 | 1.0998 | 1.0916 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.00427 | uM | 11854.156 | 1.0437 | 1.0800 | 1.0916 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.0213 | uM | 11854.156 | 0.9509 | 0.9098 | 1.0916 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.107 | uM | 11854.156 | 0.6788 | 0.4025 | 1.0916 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.533 | uM | 11854.156 | 0.7111 | 0.4634 | 1.0916 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 2.67 | uM | 11854.156 | 0.7384 | 0.5149 | 1.0916 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 13.3 | uM | 11854.156 | 0.6902 | 0.4241 | 1.0916 | |
BT-20 | TNBC | Basal A | Everolimus | MTOR | MTOR | 66.7 | uM | 11854.156 | 0.3313 | -0.2730 | 1.0916 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12056.164 | 0.9441 | 0.8804 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12056.164 | 0.8978 | 0.7817 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12056.164 | 0.8519 | 0.6842 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12056.164 | 0.7247 | 0.4162 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12056.164 | 0.6068 | 0.1707 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12056.164 | 0.6495 | 0.2592 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12056.164 | 0.6320 | 0.2228 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12056.164 | 0.5796 | 0.1146 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12056.164 | 0.2994 | -0.4510 | 0.9328 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12178.164 | 1.0391 | 1.1401 | 0.5660 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12178.164 | 1.0218 | 1.0776 | 0.5660 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12178.164 | 0.8541 | 0.5136 | 0.5660 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12178.164 | 0.8144 | 0.3915 | 0.5660 |