Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7508.074 | 0.2370 | -0.6749 | 0.7924 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7510.074 | 1.0083 | 1.0209 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7510.074 | 1.0135 | 1.0343 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7510.074 | 0.9584 | 0.8956 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7510.074 | 1.0117 | 1.0295 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7510.074 | 0.9492 | 0.8726 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7510.074 | 0.9406 | 0.8511 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7510.074 | 0.8751 | 0.6900 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7510.074 | 0.6887 | 0.2489 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7510.074 | 0.6323 | 0.1211 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7511.074 | 1.0058 | 1.0092 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7511.074 | 0.9718 | 0.9552 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7511.074 | 0.9860 | 0.9777 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7511.074 | 0.9645 | 0.9435 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7511.074 | 0.9833 | 0.9735 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7511.074 | 0.8783 | 0.8045 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7511.074 | 0.7511 | 0.5941 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7511.074 | 0.5801 | 0.2990 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7511.074 | 0.5545 | 0.2533 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7512.074 | 0.7517 | 0.4576 | 0.9022 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7512.074 | 0.9767 | 0.9483 | 0.9022 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7512.074 | 0.8279 | 0.6223 | 0.9022 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7512.074 | 0.9640 | 0.9203 | 0.9022 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7512.074 | 0.6198 | 0.1771 | 0.9022 | |
| MDA-MB-415 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7512.074 | 0.8939 | 0.7662 | 0.9022 |