Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7506.074 | 1.0087 | 1.0142 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7506.074 | 0.9797 | 0.9668 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7506.074 | 0.9449 | 0.9095 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7506.074 | 0.9036 | 0.8409 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7506.074 | 0.9467 | 0.9123 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7506.074 | 0.8945 | 0.8257 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7506.074 | 0.4651 | 0.0696 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7506.074 | 0.3696 | -0.1136 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7507.074 | 1.0585 | 1.1411 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7507.074 | 1.0110 | 1.0263 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7507.074 | 0.9823 | 0.9577 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7507.074 | 1.0117 | 1.0280 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7507.074 | 0.9470 | 0.8737 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7507.074 | 0.9715 | 0.9319 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7507.074 | 0.7384 | 0.3904 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7507.074 | 0.2534 | -0.6143 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7507.074 | 0.2334 | -0.6505 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7508.074 | 1.0178 | 1.0449 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7508.074 | 0.9772 | 0.9426 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7508.074 | 1.0206 | 1.0520 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7508.074 | 1.0093 | 1.0235 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7508.074 | 0.9900 | 0.9749 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7508.074 | 1.0111 | 1.0281 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7508.074 | 0.7893 | 0.4838 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7508.074 | 0.3394 | -0.4887 | 0.7924 |