Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7463.074 | 0.9269 | 0.6940 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7463.074 | 0.9002 | 0.5891 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7463.074 | 1.0009 | 1.0037 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7463.074 | 0.9765 | 0.8987 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7463.074 | 0.8056 | 0.2466 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7463.074 | 0.6098 | -0.3217 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7464.074 | 1.0479 | 1.1774 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7464.074 | 1.0321 | 1.1182 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7464.074 | 0.9876 | 0.9550 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7464.074 | 0.9789 | 0.9238 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7464.074 | 0.9567 | 0.8453 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7464.074 | 0.8984 | 0.6463 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7464.074 | 0.8215 | 0.3992 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7464.074 | 0.6298 | -0.1366 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7464.074 | 0.4451 | -0.5404 | 0.5504 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7466.074 | 1.0414 | 1.0852 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7466.074 | 0.9538 | 0.9051 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7466.074 | 0.9829 | 0.9648 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7466.074 | 1.0080 | 1.0165 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7466.074 | 0.9879 | 0.9752 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7466.074 | 0.8487 | 0.6896 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7466.074 | 0.3041 | -0.4119 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7466.074 | 0.0844 | -0.8426 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7466.074 | 0.0645 | -0.8806 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7467.074 | 0.9806 | 0.9688 | 1.2457 |