Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 12239.154 | 0.9750 | 0.9771 | 2.2015 | |
| HCC1806 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 12239.154 | 0.9817 | 0.9833 | 2.2015 | |
| HCC1806 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 12239.154 | 1.0264 | 1.0239 | 2.2015 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 11849.154 | 0.9348 | 0.8900 | 1.1927 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 11849.154 | 1.0344 | 1.0576 | 1.1927 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 11849.154 | 0.9414 | 0.9013 | 1.1927 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 11849.154 | 0.9523 | 0.9198 | 1.1927 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 11849.154 | 0.9685 | 0.9471 | 1.1927 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 11849.154 | 0.9550 | 0.9243 | 1.1927 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 11849.154 | 1.0213 | 1.0356 | 1.1927 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 11849.154 | 0.9635 | 0.9386 | 1.1927 | |
| HCC1937 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 11849.154 | 1.0721 | 1.1202 | 1.1927 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 11055.154 | 0.9503 | 0.9435 | 1.7768 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 11055.154 | 1.0063 | 1.0071 | 1.7768 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 11055.154 | 1.0156 | 1.0175 | 1.7768 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 11055.154 | 0.9903 | 0.9890 | 1.7768 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 11055.154 | 1.0197 | 1.0221 | 1.7768 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 11055.154 | 0.9562 | 0.9502 | 1.7768 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 11055.154 | 0.9783 | 0.9755 | 1.7768 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 11055.154 | 0.9834 | 0.9813 | 1.7768 | |
| HCC1954 | HER2amp | Basal A | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 11055.154 | 1.0388 | 1.0433 | 1.7768 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10996.154 | 0.8911 | 0.6043 | 0.5230 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10996.154 | 0.9757 | 0.9080 | 0.5230 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10996.154 | 0.9285 | 0.7354 | 0.5230 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10996.154 | 0.9185 | 0.7001 | 0.5230 |