Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10996.154 | 0.9404 | 0.7783 | 0.5230 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10996.154 | 0.9468 | 0.8015 | 0.5230 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10996.154 | 0.9319 | 0.7476 | 0.5230 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10996.154 | 0.9264 | 0.7281 | 0.5230 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10996.154 | 1.0200 | 1.0770 | 0.5230 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 12192.154 | 1.0587 | 1.2237 | 0.5377 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 12192.154 | 1.0099 | 1.0371 | 0.5377 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 12192.154 | 0.9661 | 0.8756 | 0.5377 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 12192.154 | 1.0116 | 1.0432 | 0.5377 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 12192.154 | 1.0570 | 1.2172 | 0.5377 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 12192.154 | 1.0013 | 1.0048 | 0.5377 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 12192.154 | 1.0126 | 1.0471 | 0.5377 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 12192.154 | 0.9813 | 0.9309 | 0.5377 | |
| HCC2185 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 12192.154 | 1.0388 | 1.1469 | 0.5377 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10577.142 | 0.9061 | 0.8220 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10577.142 | 0.9203 | 0.8491 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10577.142 | 0.9013 | 0.8130 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10577.142 | 0.8544 | 0.7236 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10577.142 | 0.9240 | 0.8561 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10577.142 | 0.9399 | 0.8862 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10577.142 | 0.9275 | 0.8628 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10577.142 | 0.9187 | 0.8461 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10577.142 | 0.9074 | 0.8245 | 1.0584 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10937.154 | 0.9253 | 0.9009 | 1.5291 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10937.154 | 0.9604 | 0.9479 | 1.5291 |