Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10937.154 | 0.9512 | 0.9357 | 1.5291 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10937.154 | 0.9610 | 0.9486 | 1.5291 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10937.154 | 1.0205 | 1.0267 | 1.5291 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10937.154 | 0.9271 | 0.9034 | 1.5291 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10937.154 | 0.9674 | 0.9571 | 1.5291 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10937.154 | 0.9088 | 0.8788 | 1.5291 | |
| HCC3153 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10937.154 | 1.0033 | 1.0043 | 1.5291 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10578.142 | 0.8614 | 0.8418 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10578.142 | 0.9260 | 0.9168 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10578.142 | 0.8662 | 0.8475 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10578.142 | 0.8670 | 0.8485 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10578.142 | 0.9233 | 0.9138 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10578.142 | 1.0146 | 1.0160 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10578.142 | 0.9324 | 0.9242 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10578.142 | 0.9404 | 0.9333 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10578.142 | 1.0348 | 1.0382 | 1.8112 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 11850.154 | 0.9290 | 0.9244 | 1.9115 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 11850.154 | 0.9629 | 0.9608 | 1.9115 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 11850.154 | 0.9582 | 0.9559 | 1.9115 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 11850.154 | 0.8763 | 0.8665 | 1.9115 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 11850.154 | 0.9654 | 0.9635 | 1.9115 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 11850.154 | 0.9302 | 0.9257 | 1.9115 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 11850.154 | 0.9799 | 0.9788 | 1.9115 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 11850.154 | 0.9687 | 0.9670 | 1.9115 | |
| HCC38 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 11850.154 | 1.0893 | 1.0915 | 1.9115 |