Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10873.154 | 0.9950 | 0.9914 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10873.154 | 1.0022 | 1.0038 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10873.154 | 0.9564 | 0.9249 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10873.154 | 0.9665 | 0.9423 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10873.154 | 0.9903 | 0.9833 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10873.154 | 0.9525 | 0.9182 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10873.154 | 1.0506 | 1.0866 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10873.154 | 0.9519 | 0.9171 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10873.154 | 1.0254 | 1.0435 | 1.1648 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000171 | uM | 12400.167 | 0.9786 | 0.9661 | 1.2627 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000853 | uM | 12400.167 | 0.9933 | 0.9894 | 1.2627 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00427 | uM | 12400.167 | 1.0019 | 1.0030 | 1.2627 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0213 | uM | 12400.167 | 0.9382 | 0.9015 | 1.2627 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.107 | uM | 12400.167 | 0.9802 | 0.9685 | 1.2627 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.533 | uM | 12400.167 | 1.0166 | 1.0262 | 1.2627 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 2.67 | uM | 12400.167 | 1.0045 | 1.0072 | 1.2627 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 13.3 | uM | 12400.167 | 1.0219 | 1.0346 | 1.2627 | |
| HCC70 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 66.7 | uM | 12400.167 | 1.0208 | 1.0329 | 1.2627 | |
| Hs 578T | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10694.154 | 1.0121 | 1.0105 | 2.3045 | |
| Hs 578T | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10694.154 | 0.9837 | 0.9858 | 2.3045 | |
| Hs 578T | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10694.154 | 1.0229 | 1.0197 | 2.3045 | |
| Hs 578T | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10694.154 | 1.0658 | 1.0561 | 2.3045 | |
| Hs 578T | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10694.154 | 1.0224 | 1.0193 | 2.3045 | |
| Hs 578T | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10694.154 | 1.0078 | 1.0068 | 2.3045 | |
| Hs 578T | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10694.154 | 1.0076 | 1.0066 | 2.3045 |