Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 12056.154 | 0.9599 | 0.9123 | 0.9136 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 12056.154 | 0.8751 | 0.7283 | 0.9136 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 12056.154 | 0.8981 | 0.7780 | 0.9136 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 12056.154 | 0.8860 | 0.7519 | 0.9136 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 12056.154 | 0.9150 | 0.8147 | 0.9136 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 12056.154 | 0.8621 | 0.7002 | 0.9136 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 12056.154 | 0.9386 | 0.8659 | 0.9136 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 12178.154 | 1.0702 | 1.2804 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 12178.154 | 1.0233 | 1.0912 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 12178.154 | 1.0055 | 1.0214 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 12178.154 | 1.0942 | 1.3805 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 12178.154 | 1.1394 | 1.5742 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 12178.154 | 0.9921 | 0.9694 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 12178.154 | 1.0757 | 1.3032 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 12178.154 | 0.9745 | 0.9025 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 12178.154 | 1.0135 | 1.0524 | 0.5170 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000171 | uM | 12291.167 | 0.9245 | 0.7603 | 0.6147 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000853 | uM | 12291.167 | 0.9250 | 0.7619 | 0.6147 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00427 | uM | 12291.167 | 0.9701 | 0.9036 | 0.6147 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0213 | uM | 12291.167 | 0.8914 | 0.6589 | 0.6147 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.107 | uM | 12291.167 | 0.9491 | 0.8370 | 0.6147 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.533 | uM | 12291.167 | 0.9227 | 0.7547 | 0.6147 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 2.67 | uM | 12291.167 | 0.8693 | 0.5925 | 0.6147 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 13.3 | uM | 12291.167 | 0.9038 | 0.6966 | 0.6147 | |
| BT-474 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 66.7 | uM | 12291.167 | 0.9337 | 0.7888 | 0.6147 |