Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12178.164 | 0.7709 | 0.2630 | 0.5660 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12178.164 | 0.7273 | 0.1395 | 0.5660 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12178.164 | 0.7440 | 0.1862 | 0.5660 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12178.164 | 0.7165 | 0.1098 | 0.5660 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12178.164 | 0.4408 | -0.5296 | 0.5660 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12291.156 | 0.9472 | 0.8248 | 0.5920 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12291.156 | 0.8254 | 0.4462 | 0.5920 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12291.156 | 0.8400 | 0.4899 | 0.5920 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12291.156 | 0.7280 | 0.1700 | 0.5920 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12291.156 | 0.6372 | -0.0659 | 0.5920 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12291.156 | 0.6636 | 0.0004 | 0.5920 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12291.156 | 0.5739 | -0.2173 | 0.5920 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12291.156 | 0.5902 | -0.1794 | 0.5920 | |
BT-474 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12291.156 | 0.4502 | -0.4806 | 0.5920 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 11855.156 | 1.0141 | 1.0595 | 0.4788 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 11855.156 | 1.0322 | 1.1369 | 0.4788 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 11855.156 | 0.9274 | 0.7088 | 0.4788 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 11855.156 | 0.8314 | 0.3598 | 0.4788 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 11855.156 | 0.7864 | 0.2107 | 0.4788 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 11855.156 | 0.7913 | 0.2265 | 0.4788 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 11855.156 | 0.8409 | 0.3927 | 0.4788 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 11855.156 | 0.7517 | 0.1019 | 0.4788 | |
BT-483 | HR+ | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 11855.156 | 0.2867 | -0.8529 | 0.4788 | |
BT-549 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000171 | uM | 12305.156 | 0.9135 | 0.9389 | 2.9137 | |
BT-549 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000853 | uM | 12305.156 | 0.8695 | 0.9063 | 2.9137 |