Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00427 | uM | 12414.167 | 0.9805 | 0.9678 | 1.2130 | |
| MDA-MB-453 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0213 | uM | 12414.167 | 1.0095 | 1.0157 | 1.2130 | |
| MDA-MB-453 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.107 | uM | 12414.167 | 0.9952 | 0.9920 | 1.2130 | |
| MDA-MB-453 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.533 | uM | 12414.167 | 0.9564 | 0.9277 | 1.2130 | |
| MDA-MB-453 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 2.67 | uM | 12414.167 | 0.9912 | 0.9854 | 1.2130 | |
| MDA-MB-453 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 13.3 | uM | 12414.167 | 0.9426 | 0.9049 | 1.2130 | |
| MDA-MB-453 | TNBC | Luminal | FTase Inhibitor I | Ftase | MAPK | 66.7 | uM | 12414.167 | 0.8890 | 0.8151 | 1.2130 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10644.142 | 0.9866 | 0.9486 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10644.142 | 0.9773 | 0.9130 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10644.142 | 0.9899 | 0.9609 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10644.142 | 1.0091 | 1.0355 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10644.142 | 1.0881 | 1.3552 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10644.142 | 0.9542 | 0.8264 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10644.142 | 1.0133 | 1.0518 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10644.142 | 1.0115 | 1.0447 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10644.142 | 0.9302 | 0.7386 | 0.5163 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10874.154 | 0.9722 | 0.9276 | 0.7639 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10874.154 | 1.0184 | 1.0483 | 0.7639 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10874.154 | 0.9054 | 0.7560 | 0.7639 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10874.154 | 0.9717 | 0.9263 | 0.7639 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10874.154 | 1.0086 | 1.0226 | 0.7639 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10874.154 | 0.9861 | 0.9637 | 0.7639 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10874.154 | 1.0059 | 1.0156 | 0.7639 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10874.154 | 0.9632 | 0.9041 | 0.7639 | |
| MX1 | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10874.154 | 1.0390 | 1.1026 | 0.7639 |